Oestrogen receptors in breast capsules – experimental findings

This study from Rome, on humans, is stated by the authors to be not definitive and further work is required before any treatment can be recommended. But careful analysis of oestrogen receptors in breast capsules and the number of fibroblasts...

Hyposalivation in the oral cavity

This article is a comprehensive but succinct look at the effects of hyposalivation secondary to Sjogren's syndrome in the oral cavity. These publications are divided into dental manifestations, oral mucosal manifestations and other oral manifestations. The authors discuss caries, gingivitis,...

A comparison between the American European Consensus Group and the American College of Rheumatology classification criteria for Sjogren's syndrome

This article highlights the challenges in diagnosing Sjogren's syndrome. As is pointed out in the introduction, there is no one gold standard for diagnosis and since 1965, there have been 11 sets of classification criteria for Sjogren's syndrome. The authors...

Diagnosis and management of orbital vascular malformations

This is an authoritative review of a controversial and difficult clinical area. The authors have experience of over 350 cases and provide a well-structured review of the classification and management of orbital vascular malformations. They emphasise the need to understand...

Analysis and outcome of explanted hydroxyapatite orbital implants

This is a retrospective case series over 11 years of 25 patients with exposed synthetic hydroxyapatite orbital implants who underwent explantation and simultaneous replacement with a dermis fat graft. All patients had signs of infection and had been treated with...

Case-based illustration and discussion of surgical modalities to manage traumatic hand defects

The authors present four clinical cases of soft tissue defects affecting the hand and discuss various surgical management options available. These cases include a dorsal hand wound, thumb pulp defect, first webspace defect and a volar finger defect. For each...

Use of acellular dermal matrices in revisional breast reconstruction

In this study the authors present a review of their experience in using Acellular Dermal Matrix (AlloDerm) in revision breast reconstruction procedures. They retrospectively reviewed all revisional breast reconstruction cases over a five-year period in which AlloDerm had been utilised....

Facial changes caused by smoking

Smoking is a well known factor in facial ageing. In this interesting evidence level II article, the authors have decided to evaluate the effect of smoking in monozygotic twins with different smoking histories using standarised photography. Seventy-nine pairs of twins...

Reversing signs of skin ageing with topical retinoids

The reversal of the signs of ageing / aged skin is an important component of any form of facial surgery. The authors here have written a comprehensive paper detailing the biological process in skin ageing and role of topical retinoid...

A clinical update on the management of giant congenital melanocytic naevi

The senior author (RM Zuker) presents a discussion with evidence, on the controversies and shift in the treatment paradigm for giant congenital melanocytic naevi (GCMN). On review of the current literature the overall incidence of melanoma in GCMN is 0.7...

Publish or perish

Most doctors have submitted papers and very rarely is the paper accepted outright. In fact the majority are not accepted initially. Not to worry, you are in good company. Only 9% of 6000 manuscripts submitted annually to the Journal of...

Comparing the rates of fat necrosis in irradiated muscle-sparing tram versus diep flap breast reconstruction

The authors performed a retrospective cohort study of patients undergoing immediate autologous breast reconstruction with an abdominal free flap. Over a 17-month period, 625 flaps were included in 518 patients, with 40 flaps receiving irradiation. Mean patient age and BMI...

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