This study from Rome, on humans, is stated by the authors to be not definitive and further work is required before any treatment can be recommended. But careful analysis of oestrogen receptors in breast capsules and the number of fibroblasts present suggests that possibly the anti-fibrotic role of anti-oestrogenic therapies (like Tamoxifen), decreasing the fibroblasts proliferation and contraction might lower the severity of capsular contracture. So, how long before patients, having had an augmentation, receive a shot of Tamoxifen as they leave the cowboy clinic?
Oestrogen receptors in breast capsules – experimental findings
Reviewed by Martyn Webster
Oestrogen receptor-alpha and -beta expression in breast implant capsules. Experimental findings and clinical correlates.
