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A short overview of the evolution of botulinum toxin type A formulations

Botulinum toxin type A (BoNT-A) is a potent neurotoxin produced by the bacterium Clostridium botulinum [1]. BoNT-A has been used for various therapeutic and aesthetic purposes, including the treatment of muscle disorders, chronic pain and facial wrinkles [2-4]. Over the...

Polynucleotides: A scientific explanation

This article has been verified for CPD. Click the button below to answer a few short questions and download a form to be included in your CPD folder. Introduction and background This article offers an objective analysis of a new...

How I Do It - X neo-umbilicoplasty

Following an abdominoplasty the umbilicus is repositioned and inset into a new position. When healed it should have a natural appearance and in order to get this outcome it is necessary to understand what is ‘normal’. Several different morphological appearances...

Non-surgical management of actinic keratosis, Bowen’s disease and non-melanoma skin cancer

Non-melanoma skin cancers (NMSCs) are primary cutaneous neoplasms comprising mainly of basal cell carcinomas (BCCs) and squamous cell carcinomas (SCCs). In 2011, 102,628 cases of NMSCs (74% BCC and 23% SCC) were recorded in England, making NMSC the most common...

The future and a summary of the past

From liposuction to adipose stem cells; from regenerative medicine to tissue engineering; and a vision of the future. Part 3 Adipose stem cells There is a major clinical need for strategies that adequately reconstruct the soft tissue defects after deep...

Combined procedures: lipo-abdominoplasty and lipo-inner thighplasty (string technique) and face rejuvenation

From liposuction to adipose stem cells; from regenerative medicine to tissue engineering; and a vision of the future. Part 2 With the evolution of superficial suction lipectomy in the 1990’s the need for skin resection became less common and the...

A practical guide to the most commonly used dressings in wound care

The author explores and reviews the most popular classes of dressings used for acute, chronic and problem wounds, their properties and indications based on direct observation and research studies. With an ever-increasing armamentarium of wound care tools, different brands and...

How I Do It - Approaches to acne treatment: Nd:YAG laser

Acne is common among individuals who experience a condition of hyperactive pilosebaceous units (precipitation and mobility of keratinocytes). A specific T-cell mediated inflammatory response is the initiating event in acne pathogenesis, followed by comedone formation. The mechanism of inflammation is...

Perspectives on: Polyurethane covered breast implants

The manufacturer’s viewpoint: Myths, failures and the regulation of the modern breast implant. The modern day silicone breast implant industry was created with the Dow Corning prosthesis, first used in the USA in 1962. Since its introduction into the market...

Improving cosmesis after breast implant removal

Removing breast implants has a profound effect on the patient’s appearance; in this article the authors, both expert breast surgeons, discuss how to optimise the cosmetic result. Removing breast implants has a profound effect on the patient’s appearance and we...

The new era of advanced AI-powered aesthetics

“AI is the most powerful technology force of our time.” Jensen Huang, Nvidia CEO. The 101 on AI Artificial intelligence (AI) is set to redefine our social, economic and healthcare infrastructure. Artificial intelligence represents machine learning designed to be intuitive...

A comparison of academic output of Welsh burns and plastic surgery trainees pre- and mid-COVID-19 pandemic: a cross-sectional study

The COVID-19 pandemic has affected the work of doctors worldwide, with surgical resources being diverted and non-emergency surgeries postponed. With surgical activity at 33.6% of expected levels in 2020, this sudden, vast decrease in surgical activity may have granted some...