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Botulinum toxin (BoNT) for depression: A review of the mechanism of action and its potential place as an adjuvant treatment

BoNT is becoming a recognised efficient treatment for depression, endorsed by several disciplines including psychiatry. Clare Amrani examines the potential mechanism of action and explores the appropriate place of BoNT in the therapeutic armamentarium for depression. How did BoNT become...

IMCAS China 2015

The IMCAS brand is now well established as a global leader in bringing together a multi-disciplinary, multi-professional approach to the world of ‘aesthetic surgery and cosmetic dermatology’. The first meeting was held in Paris in 1994 and was promoted as...

Rediscovering the Lost Art of Endonasal Rhinoplasty

The invention of modern rhinoplasty by Joseph transformed our understanding of nasal anatomy and surgery. His endonasal technique soon spread from Europe to the USA and dominated the surgical culture of the 20th century. The excessive removal nasal support structures...

The challenge of reinterpreting past data through the lens of advances in skin biome research

Advances in technology have allowed scientists to expand their understanding of the complex interactions that occur between humans and the microbes that reside on and inside their bodies. However, these same advances present a challenge to scientists and clinicians to...

Rhoton’s Atlas of Head, Neck, and Brain

Rhoton’s Atlas of Head, Neck ,and Brain is an all-encompassing anatomical atlas of the head and neck, ideal for surgeons, anatomists and students. The book is a collaboration amongst a group of neurosurgeons and anatomists, and it features an extensive...

Alar retraction – background and handling

The authors present a comprehensive analysis of alar retraction malformation in rhinoplasty patients. For this retrospective review they analysed 45 patients with alar-columellar disproportion. Various aetiologies were identified. Treatment of these has to be determined on an individual case-to-case basis....

Could a technology from the past change skin disinfection for the future?

It wouldn’t be unreasonable to argue that the field of medicine has seen some of the most significant scientific advances of the past 100 years: the cracking of genetic coding, the advances in pharmacology, the development of biopharmaceuticals and the...

Poor glycaemic control associated with worse outcomes in primary wound closure

This study is the first to specifically investigate the effects of chronic and perioperative glycaemic control in high risk patients undergoing primary closure of wounds. Seventy-nine patients were included – 93% of closures were of the lower limb and only...

Facial rejuvenation with the Profound RF System

Ageing of the face has become more noticeable among men and women in the modern world. The new work-from-home environment with more and more online meetings has created surroundings where people see themselves repeatedly on screen and therefore many have...

Multiple free flaps for head and neck cancer

Most patients with advanced head and neck cancers now undergo microvascular free flap reconstruction. This is mainly as flaps facilitate complete tumour and margin removal by providing reliable wound coverage and better restoration of form and function. However, despite this,...

Empowering tomorrow’s surgeons: PRASSA UK’s commitment to advancing plastic surgery awareness within the student population

In the dynamic world of medicine, one organisation stands out as a beacon for aspiring plastic surgeons – the Plastic, Reconstructive and Aesthetic Surgery Student’s Association of the United Kingdom (PRASSA UK). Born out of a passion for excellence and...

Old dogs can learn new tricks: the use of an often overlooked treatment modality for pathologically fractured mandibles

Figure 1: Timeline detailing key events in the patient’s treatment. Whilst commonly affecting the feet, spine and hips in adults, osteomyelitis (OM) can also present to the oral and maxillofacial surgery (OMFS) clinic as pathology of the jaws. Case reports...