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Reconstruction of complex wounds in the trunk and pelvis (part 1)

This is the first part of a two-part article looking at the challenges of reconstruction of complex defects in the torso. The articles are based on a presentation given at the World Union of Wound Healing Societies held in Yokohama...

Non-surgical management of actinic keratosis, Bowen’s disease and non-melanoma skin cancer

Non-melanoma skin cancers (NMSCs) are primary cutaneous neoplasms comprising mainly of basal cell carcinomas (BCCs) and squamous cell carcinomas (SCCs). In 2011, 102,628 cases of NMSCs (74% BCC and 23% SCC) were recorded in England, making NMSC the most common...

New approaches to soft tissue reconstruction involving adipose tissue engineering

Introduction The spectrum of patients affected by subcutaneous tissue loss is both wide and varied, including those who have undergone tumour removal, trauma patients, such as those injured in road traffic accidents, and individuals who have suffered from deep burns...

The three stages of breast reconstruction

Breast cancer has become so common that most people reading this article will know someone (either professionally or personally) who has been affected by breast cancer. One of the most common treatments for breast cancer is removal of the ‘whole’...

Perspectives on: Polyurethane covered breast implants

The manufacturer’s viewpoint: Myths, failures and the regulation of the modern breast implant. The modern day silicone breast implant industry was created with the Dow Corning prosthesis, first used in the USA in 1962. Since its introduction into the market...

A short overview of the evolution of botulinum toxin type A formulations

Botulinum toxin type A (BoNT-A) is a potent neurotoxin produced by the bacterium Clostridium botulinum [1]. BoNT-A has been used for various therapeutic and aesthetic purposes, including the treatment of muscle disorders, chronic pain and facial wrinkles [2-4]. Over the...

Polynucleotides: A scientific explanation

This article has been verified for CPD. Click the button below to answer a few short questions and download a form to be included in your CPD folder. Introduction and background This article offers an objective analysis of a new...

Real-world use of telemedicine – a picture is worth a thousand words

Recent advances in mobile phone camera technology and app software design have allowed photos of patients and their wounds to be sent from any smartphone to a secure NHS database, which can then be accessed by the relevant clinician with...

Filler complications: is there a way to prevent vascular compromise with 3D-anatomy?

The use of facial filler injections has increased dramatically over the last 10 years and so has the incidence of complications. The main and most serious adverse event is vascular compromise. The most feared consequences are devastating: blindness, skin necrosis...

Focus on: Cosmeceuticals (part 2)

To start the second part (see also Definitions, regulations and a review of the market and Skin anatomy and photoageing and Focus on: Cosmeceuticals (part 2) - continued) of this special focus on cosmeceuticals the authors will present some of...

Focus on Cosmeceuticals: Skin anatomy and photoageing

Skin anatomy The skin of the face provides crucial functions of temperature regulation, reparative functions following injury, facial expression, protective mechanisms against infection and ultraviolet radiation, as well as sensory perception. The integument consists of two principle layers, the epidermis...

The role of angiogenesis in wound healing, scarring and tissue regeneration

In the UK alone there are 175,000 people who visit Accident & Emergency departments with burns each year. This results in around 13,000 hospital admissions, of which 1000 are due to severe burns [1]. Over half of these admissions are...