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Aesthetic restoration following GLP-1 agonist–induced facial volume loss

GLP-1 receptor agonists such as semaglutide (Ozempic®, Wegovy®, Rybelsus®) have significantly improved the management of obesity and type 2 diabetes, providing effective weight loss and cardiometabolic benefits. However, as their use becomes more widespread, there has been an increase in...

The gender affirmation surgery MDT

The authors provide a comprehensive and thought-provoking discussion of the multidisciplinary nature of caring for someone undergoing gender reassignment surgery. In the last 50 years in the UK an estimated 130,000 people have changed their gender assigned at birth (assigned...

A short overview of the evolution of botulinum toxin type A formulations

Botulinum toxin type A (BoNT-A) is a potent neurotoxin produced by the bacterium Clostridium botulinum [1]. BoNT-A has been used for various therapeutic and aesthetic purposes, including the treatment of muscle disorders, chronic pain and facial wrinkles [2-4]. Over the...

Old dogs can learn new tricks: the use of an often overlooked treatment modality for pathologically fractured mandibles

Figure 1: Timeline detailing key events in the patient’s treatment. Whilst commonly affecting the feet, spine and hips in adults, osteomyelitis (OM) can also present to the oral and maxillofacial surgery (OMFS) clinic as pathology of the jaws. Case reports...

The applications of mesotherapy in aesthetic medicine

Mesotherapy is a modern form of therapy that consists of injecting medicines, vitamins and minerals as close as possible to the area that needs treatment. It is an astonishingly effective technique in aesthetic medicine as it treats layers of the...

In conversation with Klaus Fritz

We spoke with Dr Klaus Fritz, a board member with 5CC, about his career in dermatology and 5CC’s upcoming congress in Barcelona. Can you tell us a little bit about what led you into the field of dermatology, and what...

Treatment of rosacea using pulsed dye laser

Rosacea is a common chronic cutaneous inflammatory condition estimated to affect 415 million people worldwide [1]. It characteristically affects the central face and its primary features include flushing, non-transient erythema, telangiectasia and in progressive stages papules and pustules. Secondarily, it...

Cleft lip and palate care in low resource countries

The author explains why the traditional ‘humanitarian mission’ style of charity work needs to change and how the charity CLEFT is making an impact. It is estimated that between 150,000 and 250,000 babies are born each year worldwide with clefts...

Using erythema-directed digital photography in patients with rosacea

The authors, from the University of Catania in Italy, discuss the promise that erythema-directed digital photography is showing in the clinical evaluation and targeted treatment of rosacea. Rosacea is a common chronic inflammatory facial condition that can lead to significant...

Combination treatment of acne and pigmentation disorders

Regenerative aesthetic medicine aims to restore both the function and the structure of an ageing skin. Patients are looking for safe and subtle treatments to refresh their appearances without structural alteration or downtime. Aesthetics are often included in the management...

How I Do It - Approaches to non-surgical face lifting

PDO threads By Martyn King Polydioxanone or poly-p-dioxanone (PDO, PDS) is a colourless, crystalline, biodegradable polymer of multiple repeating ether-ester units and has been used in many disciplines of surgery as subcutaneous and cutaneous stitches for over 30 years. It...

Handy Solutions

Very few people, if any, enjoy the ravages associated with the ageing process. Apoptosis (programmed cell death) occurs throughout life, but for some unknown reason (possibly associated with epigenetics) cellular replacement and therefore matrix volume decreases. The result is that...