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A study of chronic refractory tibia osteomyelitis treated with surgery and adjuvant hyperbaric oxygen

Introduction Chronic tibial osteomyelitis is a difficult problem to eradicate and often fails to respond to surgical treatment. Orthopaedic surgeons find it difficult to treat these infections which reside as a nidus in dead bone. There is always a risk...

Body contouring surgery following massive weight loss

There are many different perceptions about what defines the term ‘overweight’. The reality is however that, for many, being overweight is a condition that brings with it significant health and social problems. It is estimated that almost two thirds of...

Cord lining mesenchymal stem cell exosomal proteins and their effects on hair follicles

Umbilical cord lining (UCL) mesenchymal stem cells (MSC) produce proteins and growth factors that, when packaged into exosomes in fixed proportions, can stimulate repair and regeneration in recipient cells. The pleiotropic properties of UCL-MSC have been shown to be effective...

Preferred upper / lower lip ratio and perception of naturally looking lips, a study across generations and genders

Introduction ‘Beauty is in the eye of the beholder’. Although it sounds true, most often some beauty patterns or preferences can be innate or intuitive [1]. When it comes to the ideal lips, how much of their features can be...

The truth behind facelift myths

As the number of non-surgical options to treat the ageing face has increased in recent years, so have the number of myths about facelift surgery. This article, from two expert facial plastic surgeons from Stanford Hospital in California, provides the...

The safety of performing elective dermatological procedures under local anaesthetic during the COVID-19 pandemic

During the first wave of the COVID-19 pandemic, guidance advised postponement of elective procedures except for time-critical local anaesthetic (LA) procedures [1-3]; our NHS Trust therefore continued with LA skin malignancy surgery. All patients having possible skin cancer lesions removed...

Filler complications: is there a way to prevent vascular compromise with 3D-anatomy?

The use of facial filler injections has increased dramatically over the last 10 years and so has the incidence of complications. The main and most serious adverse event is vascular compromise. The most feared consequences are devastating: blindness, skin necrosis...

Botulinum toxin (BoNT) for depression: A review of the mechanism of action and its potential place as an adjuvant treatment

BoNT is becoming a recognised efficient treatment for depression, endorsed by several disciplines including psychiatry. Clare Amrani examines the potential mechanism of action and explores the appropriate place of BoNT in the therapeutic armamentarium for depression. How did BoNT become...

Reconstruction of complex wounds in the trunk and pelvis (part 2)

In this second part of this two-part article we begin by looking at component separation which is a technique of reconfiguring anatomical layers to allow intrinsic reconstruction of the integrity of the anterior abdominal wall. We then move into the...