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Lymph node ratio – another predictor of outcomes in tongue SCC
Oral squamous cell carcinoma (SCC) is an increasing disease with over 263,000 diagnosed new cases and 128,000 deaths annually worldwide. Although there have been significant advances in diagnostics, surgery and anaesthetics there has been no increase in the survival rates...How I Do It - Non-surgical skin cancer treatment: topical photodynamic therapy
The incidence of skin cancer is rising exponentially in the UK; in particular non-melanoma skin cancer, yet the current statistical data surrounding exact figures is thought to be underestimated. Topical photodynamic therapy (PDT) provides a non-invasive, safe and efficacious modality...Focus on Cosmeceuticals: Skin anatomy and photoageing
Skin anatomy The skin of the face provides crucial functions of temperature regulation, reparative functions following injury, facial expression, protective mechanisms against infection and ultraviolet radiation, as well as sensory perception. The integument consists of two principle layers, the epidermis...The future of energy-based devices: do we have limits?
Victor Gabriel Clatici asks what is the final frontier in dermatology, plastic surgery and aesthetic medicine?
Significance of exterior capsular spread in a clinically negative neck
This is a retrospective paper from Zagreb of 61 patients with a clinically T1-T3 N0 squamous cell carcinoma undergoing primary surgical treatment. All patients had a level I-IIII/IV elective neck dissection. Those who had adverse histological features, including extracapsular spread,...
Combined Vismodegib and Mohs surgery
This is a report of eight patients with locally advanced periocular basal cell carcinoma who were treated with Vismodegib prior to Mohs micrographic surgery. The rationale for the combined treatment plan was that long-term Vismodegib is poorly tolerated due to...
Lymph node ratio in tongue cancer
This is an analysis of 88 patients treated in Switzerland between 2003 and 2012. All patients had a selective neck dissection and recurrence occurred in 25 patients. Overall and disease specific survival were 72% and 80%. They specifically looked at...Prednisolone and/or acyclovir for Bell’s palsy
Facial nerve paralysis as a consequence of Bell’s palsy can result in devastating long‑term effects on a patient’s appearance. What is the best medical treatment for this condition? Stuart Burrows provides his appraisal of this landmark paper from the New...
Evidence based review of management for common head and neck cancers
As part of the PRS evidence based review series, this well written review summarises the up-to-date knowledge regarding the surgical and non-surgical management of the common facial skin cancers. The review is limited to BCC, SCC, MM and Merkel Cell...Part three: Aye, Aye. AI?
I wonder whether we should use the term 'augmented intelligence' rather than 'artificial intelligence'. I say this because at this moment in our evolution, artificial intelligence (AI) always begins with human intelligence. In this blog, I want to examine how...
PRP and Microneedling in Aesthetic Medicine
Platelet rich plasma (PRP) makes sense scientifically. Platelets are a bit like biological robots. They do not have a cell nucleus, but they do have a program which directs them to surveil blood vessel walls and, in particular, to respond...
