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Botulinum toxin (BoNT) for depression: A review of the mechanism of action and its potential place as an adjuvant treatment

BoNT is becoming a recognised efficient treatment for depression, endorsed by several disciplines including psychiatry. Clare Amrani examines the potential mechanism of action and explores the appropriate place of BoNT in the therapeutic armamentarium for depression. How did BoNT become...

The use of neuromodulators in the management of TMJ disorders

The temporomandibular joint (TMJ) articulates the mandible to the base of the skull. Temporomandibular joint disorders (TMD) are a group of musculoskeletal syndromes affecting the TMJ and the supporting musculature. The muscles, bony articular surfaces and disc may all be...

Nutraceuticals and skin health

An interesting discussion on the evidence surrounding nutraceuticals. The author describes nutracosmetics to be one of the fastest growing subsections of the nutraceutical industry. A comprehensive analysis of topical and dietary antioxidant protection is conveyed with conclusive evidence to demonstrate...

Gross Negligence Manslaughter in Healthcare: The medico-legal dilemma (part 4)

I want to return to the case of Dr Mak, who was, from the available evidence, caught up in a miscarriage of justice that arose because of a lack of effective interprofessional communication in the legal process.

We need to talk about amputation – a difficult conversation in the developing world

What do you do when a patient refuses amputation? The author shares various cases and outlines her team’s approach to this scenario in Gaza. What to do when a patient refuses amputation for a severely damaged lower limb that will...

How I Do It - Body contouring

Unwanted fat, cellulite and skin flaccidity are three of the top reasons for consultation in aesthetic medical practices, with body remodeling treatments using non-invasive techniques increasingly in demand. The TightSculpting treatment with the Fotona SP Dynamis laser allows practitioners to...

How I Do It - Treating the lower face with HA fillers in elderly patients

Facial rejuvenation treatment of the lower third of the face with hyaluronic acid (HA) fillers in elderly patients can result in the development of fibrous tissue especially after several procedures have been performed. Many patients present with concerns over the...

Immediate versus delayed post mastectomy breast reconstruction

The authors review and analyse the current literature comparing the psychosocial outcomes of immediate versus delayed post mastectomy breast reconstruction. Breast cancer is the most prevalent cancer in women and has a lifetime incidence of one in nine. Mastectomy may...

Gross Negligence Manslaughter in Healthcare: The medico-legal dilemma (part 23) - Snoring

We all know what snoring is, but do we understand what snoring means?

Postoperative follow-up of oral squamous cell carcinoma: a new protocol

Oral and oropharyngeal cancers together are the sixth most common malignancy in the world, with an increasing incidence of oral squamous cell carcinoma (OSCC). The recurrence rate of OSCC is reported to be approximately 10-26%. About two-thirds of all recurrent...

Classification and assessment of midfacial fractures: no more Le Fort facial fractures

There is some evidence that severe or complex midfacial or orbital fractures have declined over the last decade. Interestingly there is also evidence of an increase in road traffic accidents but a decrease in facial injuries. This is possibly attributed...

Extracutaneous Merkel cell carcinoma or metastatic Merkel cell carcinoma with an occult primary?

Merkel cell carcinoma (MCC) is a rare and aggressive malignancy arising from dermal neuroendocrine cells, first described by Toker in 1972 [1]. It is predominately seen in the head and neck region of older, white males and risk factors include...