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The role of angiogenesis in wound healing, scarring and tissue regeneration
In the UK alone there are 175,000 people who visit Accident & Emergency departments with burns each year. This results in around 13,000 hospital admissions, of which 1000 are due to severe burns [1]. Over half of these admissions are...
The use of platelet-rich plasma in skin flap grafts
This study was conducted to evaluate the ability of platelet rich plasma (PRP) to stimulate angiogenesis following skin flaps graft surgery, and its effect on flap survival rate. The use of PRP to improve the quality of bone regeneration and...Chronic telogen effluvium reversal using E. coli-derived cytokines and growth factors: a case report
Chronic telogen effluvium (CTE) is a condition where there is prolonged increased hair shedding, primarily affecting middle-aged women. Its exact cause is often unknown. In CTE, many hair follicles enter the resting phase prematurely due to various reasons, leading to...Tranexamic acid and platelet rich plasma in the treatment of melasma: efficacy and safety
Melasma is a common, acquired, progressive, often symmetrical macular hypermelanosis that is usually localised on the face and more frequently on the forehead, upper lip, central and malar area of the face. It is triggered by a variety of factors,...Exosomes: everything you always wanted to know and questions to ask your exosome provider
This article has been verified for CPD. Click the button below to answer a few short questions and download a form to be included in your CPD folder. What are exosomes? Exosomes are just one subset of extracellular vesicles (EVs),...The efficacy of polynucleotide injections in aesthetic medicine: a review
Polynucleotide (PN) injections have gained significant attention in aesthetic medicine due to their beneficial effects on the skin, hair, and other tissues. This review explores the current evidence supporting the use of PN injections for various aesthetic concerns. Introduction Aesthetic...
Application of substance P as an osteogenitor in mandibular distraction osteogenesis
In this well organised study the authors demonstrate the benefit of use of substance P to improve the quality of bone during mandibular distraction. Substance P is a neuropeptide that is distributed in those sensory nerve fibres that innervate the...How I Do It - Hyperdilute CaHA for the ageing neck
Calcium hydroxylapatite (CaHA) has demonstrated strong biostimulatory effects; increasing collagen and elastin production, while promoting angiogenesis and proteoglycan formation [1]. Consequently, its application as a valuable aesthetic intervention for age-related skin changes is being increasingly adopted. At particular dilutions (when...
Platelet-rich plasma from androgenetic alopecia: a pilot study
The authors demonstrate some encouraging results in this pilot study, exploring the benefit of injecting platelet rich plasma (PRP) into the scalp on patients with androgenetic alopecia. This suggests the need to now proceed with a randomised control study to...
Long-term follow-up of maxillary advancement in cleft palate cases
Twenty-two consecutive patients with cleft lip and palate, treated with maxillary advancements and distraction osteogenesis, were followed up for between five and 13 years. They were divided into two groups, those who were still growing and those whose growth was...
