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Botulinum toxin (BoNT) for depression: A review of the mechanism of action and its potential place as an adjuvant treatment

BoNT is becoming a recognised efficient treatment for depression, endorsed by several disciplines including psychiatry. Clare Amrani examines the potential mechanism of action and explores the appropriate place of BoNT in the therapeutic armamentarium for depression. How did BoNT become...

IN RESPONSE TO: From PIP to DC-CIK to the Sorcerer’s Apprentice: a medico-political minefield

I am a consultant musculoskeletal physiotherapist of 20 years and I hold (2002) a masters accredited diploma in injection therapy (steroid and local anaesthetic injection techniques) as well as certificates to advanced level in cosmetic injection – dermal filler and...

A plea for reconstructive plastic surgery in the routine care of sarcoma patients

The authors from the Mayo Clinic demonstrate the advantage of early intervention by plastic surgeons in the care of patients with sarcoma. A retrospective case study review looks at the wound complication rate of surgery for those patients who have...

My experience of setting up a nurse-led independent aesthetics and dermatology clinic

An experienced nurse shares her tips and advice for launching an independent private aesthetic clinic. LoveSkin Clinic opened its doors in November 2016. Like so many other nurses embarking on such a venture I had no experience running a business...

Facial reconstruction with polyethylene implants

Planning reconstructive surgery for complex craniofacial defects challenges even the most experienced of surgeons. In most cases surgery is undertaken to improve anatomical functioning. However, the anatomical structure of these regions is also critical to facial aesthetics and patient satisfaction...

CQC regulators and private hospitals need more common sense

There is a fundamental flaw in the way regulatory bodies are allowed to pressure and scare perfectly functioning private hospitals. Invariably the regulators themselves are of ordinary stock and have to justify their salaries by increasing administrative workloads on others....

The Linear Bolus Technique and other practical tips for the advanced use of non-traumatic cannulas in aesthetic medicine

Some eight years ago, I read about non-traumatic cannulas in the brochure of a French medical supplies company. I was fascinated by the elegance of these instruments, as they respect the integrity of the tissues by not cutting through them....

Poor glycaemic control associated with worse outcomes in primary wound closure

This study is the first to specifically investigate the effects of chronic and perioperative glycaemic control in high risk patients undergoing primary closure of wounds. Seventy-nine patients were included – 93% of closures were of the lower limb and only...

Liposuction – the evolution of the classical technique

From liposuction to adipose stem cells; from regenerative medicine to tissue engineering; and a vision of the future. Part 1 The history of attempts to sculpture fat dates back to the beginning of the 20th century, but Professor Yves-Gerard Illouz...

How I Do It - Photoageing treatment: RF microneedling

Microneedling is a process by which very small, sharp needles are inserted into the skin layers at various predetermined depths to cause micro-injury to the dermis. The epidermal layer is minimally disrupted and healing is achieved without inducing an inflammatory...

Publish or perish

Most doctors have submitted papers and very rarely is the paper accepted outright. In fact the majority are not accepted initially. Not to worry, you are in good company. Only 9% of 6000 manuscripts submitted annually to the Journal of...

Making Decisions and Avoiding Complications in Skin Flaps

Whereas modern readings on reconstructive surgery impress by their high-quality graphic illustrations on heavy glossy paper next to lengthy discussions, this book has a remarkably unpretentious appearance. At first glance it becomes clear that the reader should not expect a...