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PD-1 and PD-L1 in exenteration specimens

This is an immunohistochemical study looking at variation in the expression of the programmed death-1 receptor (PD-1) and the programmed cell death ligand-1 (PD-L1), comparing cutaneous malignancies which invaded the orbit with uncomplicated nodular basal cell carcinomas. The authors retrospectively...

IgG4-related disease or Graves orbitopathy

This is a retrospective review of patients who had been diagnosed with both IgG4-related ophthalmic disease (IgG4-ROD) and Graves orbitopathy over a four-year period. Eight patients were identified. The diagnosis of IgG4-ROD was based on 10 or more IgG4+ plasma...

Imaging accurately predicting the need for mandibular resection

This is an article from Australia of 109 patients, 83 of which had CT, 72 MRI and the presence of bone invasion on imaging was compared with the histopathology. Bone invasion was present in 44 of 109 resection specimens. Bone...

Combination treatment with PN-HPT® and croma revitalis®

The rise in interest and demand from patient and medical practitioners in skin quality and associated regenerative treatment modalities continues [1]. Polynucleotides, specifically High-Purification Technology (PN-HPT®), are among some of the most popular regenerative medical treatment approaches [2]. The mode...

Extensive bilateral fat necrosis of the breast associated with the Covid-19 vaccination

Fat necrosis can occur at any site in the body; the majority of cases are in the breast and are idiopathic. Other aetiologies include trauma, fine needle aspiration cytology (FNAC), both cosmetic and therapeutic surgical procedures, autologous lipofilling of the...

Nordlys® System – Treatment of inflammatory acne and rosacea

Acne vulgaris is a common chronic inflammatory skin condition and the eighth most prevalent skin disorder worldwide, with a prevalence of 9.4% [1]. Rosacea is also a common chronic inflammatory skin disorder, with an estimated global prevalence of 5.46% of...

Lips and the perioral area: anatomical considerations for safer and natural results

This article has been verified for CPD. Click the button below to answer a few short questions and download a form to be included in your CPD folder. Minimally invasive cosmetic procedures, including lip augmentation using hyaluronic acid dermal fillers,...

How I Do It - Peri-orbital rejuvenation using HA fillers

The peri-orbital region is the first to show signs of ageing due to thin skin and changes in texture, colour and volume. This can make the eyes look tired or sunken which can have a negative impact on the global...

Extracutaneous Merkel cell carcinoma or metastatic Merkel cell carcinoma with an occult primary?

Merkel cell carcinoma (MCC) is a rare and aggressive malignancy arising from dermal neuroendocrine cells, first described by Toker in 1972 [1]. It is predominately seen in the head and neck region of older, white males and risk factors include...

Combined procedures: lipo-abdominoplasty and lipo-inner thighplasty (string technique) and face rejuvenation

From liposuction to adipose stem cells; from regenerative medicine to tissue engineering; and a vision of the future. Part 2 With the evolution of superficial suction lipectomy in the 1990’s the need for skin resection became less common and the...

CCR 2023

Join the future of Medical Aesthetics at CCR 2023 Brought to you by Aesthetics and dedicated to raising industry standards and driving innovation, CCR focuses on training practitioners and championing evidence-based research. Taking place at ExCeL, London, discover world-class educational...

Gender Affirmation – Medical & Surgical Perspectives

This book is one of the few, well-written books aimed at clinicians and surgeons with an interest in the field of gender affirmation (reassignment). It is concise and comprehensive. The authors of the chapters are international leaders in their respective...