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A short overview of the evolution of botulinum toxin type A formulations

Botulinum toxin type A (BoNT-A) is a potent neurotoxin produced by the bacterium Clostridium botulinum [1]. BoNT-A has been used for various therapeutic and aesthetic purposes, including the treatment of muscle disorders, chronic pain and facial wrinkles [2-4]. Over the...

The applications of mesotherapy in aesthetic medicine

Mesotherapy is a modern form of therapy that consists of injecting medicines, vitamins and minerals as close as possible to the area that needs treatment. It is an astonishingly effective technique in aesthetic medicine as it treats layers of the...

Lasers and the skin

Laser is an acronym for Light Amplification by Stimulated Emission of Radiation. Lasers have revolutionised the treatment of many skin conditions and are being used both in terms of a medical and an aesthetic context. Laser technology has been advancing...

Cryolipolysis: a review of published clinical data

Definition: Cryolipolysis is derived from the greek language, describing ‘cold’ and ‘fat breakdown’. History The actual phenomenon of cold induced adipocyte necrosis was originally described by Epstein et al. in 1970 who had reported the presence of a “red indurated...

Extracutaneous Merkel cell carcinoma or metastatic Merkel cell carcinoma with an occult primary?

Merkel cell carcinoma (MCC) is a rare and aggressive malignancy arising from dermal neuroendocrine cells, first described by Toker in 1972 [1]. It is predominately seen in the head and neck region of older, white males and risk factors include...

What to look for in new exosome products: A guide to the exosome cosmetic market

Exosomes have become increasingly trendy in the cosmeceutical market, not only as the latest buzzword but also in alignment with the growing trend towards natural beauty. By harnessing the regenerative potential of exosomes and incorporating them into daily skincare routines...

Liposuction – the evolution of the classical technique

From liposuction to adipose stem cells; from regenerative medicine to tissue engineering; and a vision of the future. Part 1 The history of attempts to sculpture fat dates back to the beginning of the 20th century, but Professor Yves-Gerard Illouz...