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Botulinum toxin (BoNT) for depression: A review of the mechanism of action and its potential place as an adjuvant treatment

BoNT is becoming a recognised efficient treatment for depression, endorsed by several disciplines including psychiatry. Clare Amrani examines the potential mechanism of action and explores the appropriate place of BoNT in the therapeutic armamentarium for depression. How did BoNT become...

Reconstruction of complex wounds in the trunk and pelvis (part 1)

This is the first part of a two-part article looking at the challenges of reconstruction of complex defects in the torso. The articles are based on a presentation given at the World Union of Wound Healing Societies held in Yokohama...

Hair regeneration in menopausal and androgenetic alopecia patients using PTT-6® exosomal proteins

Hair loss is a prevalent but under-recognised concern among menopausal women, often resulting in diminished self-esteem and psychological distress. Estimates suggest that over 50% of women will experience some degree of hair thinning or loss by the age of 50,...

Imaging and histological relationship of orbital schwannomas

This is a retrospective review of 15 patients with orbital schwannomas comparing the radiological characteristics, in particular the signal intensity on MRI with the histological sub-types of the tumours. Five patients had MRI imaging alone, three had CT alone and...

Risk factors for loco regional recurrence for oral SCC

Over a quarter of a million cases of oral squamous cell carcinomas (SCC) are diagnosed annually worldwide with 128,000 registered deaths. In spite of much-improved anaesthetic and surgical techniques, survival rates have not improved much over the past three decades....

OPINION - From ethics to commerce: challenges faced by cosmetic practice for 2025 and beyond

Cosmetic medicine and surgery have seen remarkable and ongoing increases in popularity, reflecting advancements in medical technology and evolving societal norms based on, for example, social media, cultural expectations, and globalisation of beauty standards. Unlike with other medical specialties, these...

The Bottom Line: buttock augmentation

The first use of silicone implants for buttock augmentation was by Bartels et al. in 1969 [1]. We must acknowledge the innovative and imaginative brilliance of the Brazilians and the descriptive detail of other surgeons, but especially Mendietta for the...

Could epidermal grafting be the solution to vitiligo?

Dr Foutsizoglou shares his thoughts on a recent innovation based on epidermal grafting that could be used on vitiligo patients. I attended the ‘Make Better Summit Meeting’, an international surgical congress organised by Acelity™ and chaired by Professor Dr med....

Cheek augmentation from A to Z

An outline of facial assessment principles and anatomical considerations regarding augmenting the cheek and mid-face is explored. Background statistics are stated regarding the number of injectable procedures performed, referenced to American Society for Aesthetic Plastic Surgery (ASAPS) data, 2016. Attention...

In conversation with Dr Emanuele Bartoletti (2019)

We were delighted to catch up with Dr Emanuele Bartoletti, President of Società Italiana di Medicina Estetica (SIME) about this background and his thoughts on the importance of medical education. Dr Emanuele Bartoletti Can you tell us a bit about...

A review on contemporary options for facial reanimation

This paper is an up-to-date review on surgical and non-surgical options for the treatment of facial paralysis. The authors thoroughly describe recent techniques, like the masseter-to-facial nerve transfer, explaining the advantages over other more popular transfer techniques like the hypoglossal-to-facial...

Facial reconstruction with polyethylene implants

Planning reconstructive surgery for complex craniofacial defects challenges even the most experienced of surgeons. In most cases surgery is undertaken to improve anatomical functioning. However, the anatomical structure of these regions is also critical to facial aesthetics and patient satisfaction...