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Cord lining mesenchymal stem cell exosomal proteins and their effects on hair follicles

Umbilical cord lining (UCL) mesenchymal stem cells (MSC) produce proteins and growth factors that, when packaged into exosomes in fixed proportions, can stimulate repair and regeneration in recipient cells. The pleiotropic properties of UCL-MSC have been shown to be effective...

Progressive peri-orbital swelling over three years: a rare complication of HA dermal filler injection treated successfully by hyaluronidase

The term ‘tear trough’ was first introduced by Flowers in 1969 to describe the deformity that leads to lower eyelid depression. It was proposed that the defect was due to a muscular defect between the angular head of the quadrates...

Treatment of facial subcutaneous fibrosis with hyaluronic acid

This article has been verified for CPD. Click the button below to answer a few short questions and download a form to be included in your CPD folder. Systemic sclerosis (SSc) is a rare and chronic connective tissue disease (CTD)...

Gross Negligence Manslaughter in Healthcare: The medico-legal dilemma (part 13) – Records of necessary information

Today is the first day of the Chinese New Year. This is the year of the Tiger. I am fine, I am a Dragon. This is going to be an interesting year.

In conversation with Dr Peter Shumaker

“The views expressed in this interview are those of the member and do not necessarily reflect the official policy or position of the Department of the Navy, Department of Defense, or the United States government.” Dr Peter Shumaker, Chairman of...

PRP and Microneedling in Aesthetic Medicine

Platelet rich plasma (PRP) makes sense scientifically. Platelets are a bit like biological robots. They do not have a cell nucleus, but they do have a program which directs them to surveil blood vessel walls and, in particular, to respond...

An epidemic of lower limb gunshot injuries

As the COVID-19 pandemic continues to impact upon us all, the author, a reconstructive plastic surgeon, provides a thought-provoking account of a different type of epidemic that is having devastating consequences. The Oxford English Dictionary defines an epidemic as “a...

The original suture suspension necklift before the i-guide

In this excellent issue of the Clinics in Plastic Surgery the topic of neck lifting is discussed. This covers the assessment, non-surgical management, minimally invasive techniques and open techniques. This invited paper looks into the authors’ experience of suture suspension...

Vascular complications part 2: management

- VIDEO CONTENT AT BOTTOM OF ARTICLE - Vascular complications from the use of soft tissue fillers can be devastating. In the second of a two-part series (click here for Part 1), the authors discuss how to manage these adverse...

A Timeline of Plastic Surgery

Where did the name ‘plastic’ surgery come from? It is probable that the first use of the term was by the German von Graefe in his book Rhinoplastik published in 1818. The intention was to describe the moulding of tissue...

Non-surgical rhinoplasty

Some patients would like to alter the appearance of their nose without surgery or make further subtle changes after a rhinoplasty. Lydia Badia explains how this can be done, thanks to injectable fillers.

Preservation rhinoplasty

Hump reduction and osteotomies to close the open roof, or lowering the whole nasal dorsum? Charles East explains how preservation techniques can improve outcomes by maintaining the integral structures of the nose. What is preservation rhinoplasty? The origins of reduction...