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Cord lining mesenchymal stem cell exosomal proteins and their effects on hair follicles

Umbilical cord lining (UCL) mesenchymal stem cells (MSC) produce proteins and growth factors that, when packaged into exosomes in fixed proportions, can stimulate repair and regeneration in recipient cells. The pleiotropic properties of UCL-MSC have been shown to be effective...

Non-surgical management of actinic keratosis, Bowen’s disease and non-melanoma skin cancer

Non-melanoma skin cancers (NMSCs) are primary cutaneous neoplasms comprising mainly of basal cell carcinomas (BCCs) and squamous cell carcinomas (SCCs). In 2011, 102,628 cases of NMSCs (74% BCC and 23% SCC) were recorded in England, making NMSC the most common...

Focus on Cosmeceuticals: Skin anatomy and photoageing

Skin anatomy The skin of the face provides crucial functions of temperature regulation, reparative functions following injury, facial expression, protective mechanisms against infection and ultraviolet radiation, as well as sensory perception. The integument consists of two principle layers, the epidermis...

Topical phenytoin effect on pressure ulcers healing: A literature review of the evidence

A pressure ulcer (PU) is a localised injury to the skin and / or underlying tissue usually over a bony prominence, because of pressure, or pressure in combination with shear (EPUAP/ NPUAP 2009/PPPPIA 2014). Bennett et al. [1] claimed total...

Post-infusion iron extravasation: Cutaneous complications and management strategies

Intravenous iron infusion is widely used for the treatment of iron-deficiency anaemia, especially in cases where oral supplementation is ineffective or contraindicated. Although generally well tolerated, iron infusion may be complicated by local adverse events, among which iron extravasation is...