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We need to talk about amputation – a difficult conversation in the developing world

What do you do when a patient refuses amputation? The author shares various cases and outlines her team’s approach to this scenario in Gaza. What to do when a patient refuses amputation for a severely damaged lower limb that will...

A short overview of the evolution of botulinum toxin type A formulations

Botulinum toxin type A (BoNT-A) is a potent neurotoxin produced by the bacterium Clostridium botulinum [1]. BoNT-A has been used for various therapeutic and aesthetic purposes, including the treatment of muscle disorders, chronic pain and facial wrinkles [2-4]. Over the...