PD-1 and PD-L1 in exenteration specimens

This is an immunohistochemical study looking at variation in the expression of the programmed death-1 receptor (PD-1) and the programmed cell death ligand-1 (PD-L1), comparing cutaneous malignancies which invaded the orbit with uncomplicated nodular basal cell carcinomas. The authors retrospectively...

Imaging and histological relationship of orbital schwannomas

This is a retrospective review of 15 patients with orbital schwannomas comparing the radiological characteristics, in particular the signal intensity on MRI with the histological sub-types of the tumours. Five patients had MRI imaging alone, three had CT alone and...

A possible role for adipose tissue-derived stem cells in modulation of keloid scarring

Keloid scarring remains a challenging clinical problem due to both resistance to treatment as well as high rates of recurrence. Research into possible treatments is also hindered by keloid scarring being a uniquely human phenomenon. Recent evidence supports a role...

The FLIR ONE thermal imager for the assessment of burn wounds

The authors look at a new system called the FLIR ONE thermal imager in the assessment of burn wound depth. This is a small, handheld device with two cameras that can be attached to iOS or android tablets or smartphones....

The use of intense pulsed light therapy in the treatment of acne vulgaris

Intense pulsed light (IPL) is discussed in relation to its application in acne vulgaris. The author acknowledges that it may not be the most effective, or the first line therapy for managing such a challenging and persistent skin condition, but...

Frontal and lateral facial attractiveness

The authors examined the association between frontal and lateral facial attractiveness and identified anatomical features that may influence discordance between frontal and lateral facial beauty. They studied paired frontal and lateral facial synthetic images of 240 white women by using...

Modified anterior septal transplant

The authors describe an anterior septal graft technique, which consists of complete resection of the caudal septum and reconstruction with extended spreader grafts and a columellar strut, without a separate caudal septal replacement graft. This study was a retrospective case...

Cheek augmentation from A to Z

An outline of facial assessment principles and anatomical considerations regarding augmenting the cheek and mid-face is explored. Background statistics are stated regarding the number of injectable procedures performed, referenced to American Society for Aesthetic Plastic Surgery (ASAPS) data, 2016. Attention...