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PD-1 and PD-L1 in exenteration specimens

This is an immunohistochemical study looking at variation in the expression of the programmed death-1 receptor (PD-1) and the programmed cell death ligand-1 (PD-L1), comparing cutaneous malignancies which invaded the orbit with uncomplicated nodular basal cell carcinomas. The authors retrospectively...

Imaging and histological relationship of orbital schwannomas

This is a retrospective review of 15 patients with orbital schwannomas comparing the radiological characteristics, in particular the signal intensity on MRI with the histological sub-types of the tumours. Five patients had MRI imaging alone, three had CT alone and...

The lateral neck cystic mass – diagnostic dilemma

Solitary cystic masses in the lateral neck can present a significant diagnostic dilemma. These cystic masses often develop in young adults distinguishing a branchial cleft cyst from a cystic lymph node with imaging and even high-quality fine needle aspiration cytology...

Facelifting after radiotherapy for head and neck tumours

This paper sought to determine whether facelifting in patients with prior radiotherapy for head and neck cancer was safe. This study focuses on a small sample of 16 patients matched to controls who were retrospectively assessed for major surgical morbidity....

Lymph node ratio – another predictor of outcomes in tongue SCC

Oral squamous cell carcinoma (SCC) is an increasing disease with over 263,000 diagnosed new cases and 128,000 deaths annually worldwide. Although there have been significant advances in diagnostics, surgery and anaesthetics there has been no increase in the survival rates...

Method of surgical resection affects reporting of margins of tumours in the oral cavity

It is important to obtain tumour-free resection margins in patients with oral cancer. Pathological processing is known to cause tissue to shrink, which affects the reported margins, and it is postulated that the method of resection also has an effect....

Conjunctival mapping biopsies in sebaceous carcinoma

This is a retrospective review of conjunctival mapping biopsies in patients with periocular sebaceous cell carcinoma. The authors reviewed the biopsy technique and outcomes of 45 patients who had mapping biopsies performed over a 25-year period. A total of 429...

An overview of microsurgical reconstruction of the head and neck worldwide

Microsurgical reconstruction is an integral part of the treatment following ablation for malignancy or trauma. Currently there are no clear treatment guidelines following tumour resection. This was recognised a few years ago and in 2008 various collaborative groups were founded...

Surgical indications for infantile haemangiomas

Infantile haemangiomas (IHs) are embryonic tumours and represent the most common tumour of infancy, with an estimated incidence of 4-5%. There is a well described natural history, usually becoming apparent in the first few weeks of life and proliferating rapidly,...

A conservative approach to treat ameloblastoma

Ameloblastoma is a relatively rare odontogenic tumour that is benign but locally aggressive. Additionally they tend to recur locally. These are rare accounting for 1% of oral tumours and occur almost exclusively in the jaws. It is more common in...