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New approaches to soft tissue reconstruction involving adipose tissue engineering

Introduction The spectrum of patients affected by subcutaneous tissue loss is both wide and varied, including those who have undergone tumour removal, trauma patients, such as those injured in road traffic accidents, and individuals who have suffered from deep burns...

From PIP to DC-CIK to the Sorcerer’s Apprentice: a medico-political minefield

Poly Implant Prothese (PIP) was a French company that manufactured silicone breast implants that were surgically implanted mainly for cosmetic breast augmentation. Of note, ‘cosmetic’ is used in the strict sense of the word meaning false and artificial and does...

A short overview of the evolution of botulinum toxin type A formulations

Botulinum toxin type A (BoNT-A) is a potent neurotoxin produced by the bacterium Clostridium botulinum [1]. BoNT-A has been used for various therapeutic and aesthetic purposes, including the treatment of muscle disorders, chronic pain and facial wrinkles [2-4]. Over the...