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The importance of nitric oxide in medicine

The harmful effects exerted upon living and injured tissues by free radicals have been explored since the 1980s. Now in 2021 the free radical nitric oxide (NO) is not just a figment of imagination; it is known as one of...

Differences between compounded BHRT and conventional HRT

Can BHRT offer hope to women suffering from debilitating menopausal symptoms? Ruth Crofford, ‘the menopause nurse’, explores the evidence, safety issues and misconceptions around the therapy. Life expectancy for women in the UK is currently 80.96 years [1]. Females in...

Extracutaneous Merkel cell carcinoma or metastatic Merkel cell carcinoma with an occult primary?

Merkel cell carcinoma (MCC) is a rare and aggressive malignancy arising from dermal neuroendocrine cells, first described by Toker in 1972 [1]. It is predominately seen in the head and neck region of older, white males and risk factors include...

Stem cells in reconstructive surgery: a bright but cautious future

Regenerative medicine using stem cell technology is slowly becoming a reality in routine clinical practice especially in the field of tissue regeneration [1]. It is therefore not surprising that stem cell technology is starting to be of interest in reconstructive...

Oral supplementation for skin health and rejuvenation

Lauren Jamieson explores the increasing evidence behind the role of supplements in skin health – an exciting development in the world of aesthetic medicine. The fact that lifestyle factors – and diet most especially – have a profound influence on...

Photorejuvenation: Light & Bright™ treatment for enhanced skin quality

Improving skin quality has emerged as a significant trend in recent years, driven by the synergy between at-home skincare routines and diverse aesthetic procedures administered by medical professionals. With sun-induced skin damage manifesting early in life, there’s a surging demand...

Peeling away the years: bespoke framework technique for using Definisse™ Peel Program from RELIFE in acne

Acne vulgaris is the most common potentially scarring skin condition seen in dermatology and general practice. A recent network metanalysis [1] confirmed the efficacy of oral pharmacological therapies but questioned the consistency of effect of topical agents and peels. Factors...

Treatment of chrono and photoageing with combined light sources

Skin ageing depends on various intrinsic (chronological) and extrinsic (ambiental) factors: chrono and photoageing changes include wrinkles, abnormal pigmentation, skin laxity and telangiectasia. The Nordlys™ system is a multi-platform device that incorporates dual-filtering Selective Waveband Technology (SWT®) and two fractional,...

Locked or unlocked

This is as systematic review and meta-analysis from the Netherlands, evaluating postoperative complications of mandibular fractures using locking and non-locking systems. It is suggested that postoperative complications of surgical treatment of mandibular fractures occur in 20-26% of patients, and it...

Tissue engineered flaps

This article provides a thorough summary of the current techniques available in head and neck reconstruction. It details the challenge of restoration of form and function posed by the shape of the craniofacial skeleton and soft tissue. The introduction on...

Sushruta and Indian rhinoplasty

Vijay Pothula explains rhinoplasty’s roots in ancient Indian Ayurvedic medicine, and how it was introduced to the Western world. In 1794 The Gentleman’s Magazine published a surgical operation which was long established in India but unknown in Europe [1]. A...

How I Do It - Performing a mastopexy or reduction using Breform™ mesh

Gravity defying breast surgery – the Holy Grail for breast surgeons. Repeat ptosis and pseudoptosis are significant problems facing patients and surgeons after breast reduction and mastopexy. Further surgery to correct this can be challenging, with increased complications, and the...