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Lacrimal gland carcinoma

This is a major review of the management of lacrimal gland carcinoma, focusing mainly on adenoid cystic carcinoma. Relevant literature published in English since 1970 was included amounting to some 40 articles after filtering. Overall mortality for all lacrimal gland...

Lacrimal gland carcinoma outcomes

This is retrospective review of outcomes of lacrimal gland epithelial tumours treated between 1972 and 2014 at Moorfields Eye Hospital. Seventy-nine patients were reported, comprising 53 adenoid cystic carcinomas, 15 primary adenocarcinomas and 11 carcinomas ex-pleomorphic adenoma. The authors compare...

CD73 in aggressive basal cell carcinoma

This is a retrospective review looking at levels of CD73 in aggressive basal cell carcinomas (BCCs) that invade the orbit. Eleven patients who underwent orbital exenteration for invasion by BCCs were compared with 10 matched controls who had simple nodular...

Conjunctival mapping biopsies in sebaceous carcinoma

This is a retrospective review of conjunctival mapping biopsies in patients with periocular sebaceous cell carcinoma. The authors reviewed the biopsy technique and outcomes of 45 patients who had mapping biopsies performed over a 25-year period. A total of 429...

Treatment of low-risk basal cell carcinoma and actinic

The first paper of this topic explored skin cancer recognition, patient education and sun safety. The second part focused on practical guidance for aesthetic nurses, should a patient present with a suspicious skin lesion. The author maintains that aesthetic nurses...

Postoperative follow-up of oral squamous cell carcinoma: a new protocol

Oral and oropharyngeal cancers together are the sixth most common malignancy in the world, with an increasing incidence of oral squamous cell carcinoma (OSCC). The recurrence rate of OSCC is reported to be approximately 10-26%. About two-thirds of all recurrent...

PD-1 and PD-L1 in exenteration specimens

This is an immunohistochemical study looking at variation in the expression of the programmed death-1 receptor (PD-1) and the programmed cell death ligand-1 (PD-L1), comparing cutaneous malignancies which invaded the orbit with uncomplicated nodular basal cell carcinomas. The authors retrospectively...

Periocular sweat gland carcinomas

This is an interesting review of a rare group of tumours which together comprise the adnexal sweat gland carcinomas. Although there are only 22 patients, this is the largest cohort ever published. The authors summarise the clinical presentation, stage, management...

Electrochemotherapy for BCCs

A remarkable account of an effective non-surgical treatment for basal cell carcinomas (BCCs). Electrochemotherapy (ECT) consists of making the area surrounding the lesion temporarily permeable using electric pulses (under local anaesthesia), then bleomycin is administered to the area. The treatment...

Risk factors for loco regional recurrence for oral SCC

Over a quarter of a million cases of oral squamous cell carcinomas (SCC) are diagnosed annually worldwide with 128,000 registered deaths. In spite of much-improved anaesthetic and surgical techniques, survival rates have not improved much over the past three decades....

Excisional margins for cutaneous malignancies

The authors present the results of a retrospective study of 495 non melanoma skin cancer (NMSC) lesions of the face treated with Mohs micrographic surgery (MMS) over a six year period. The size of the lesion was calculated as the...

Significance of exterior capsular spread in a clinically negative neck

This is a retrospective paper from Zagreb of 61 patients with a clinically T1-T3 N0 squamous cell carcinoma undergoing primary surgical treatment. All patients had a level I-IIII/IV elective neck dissection. Those who had adverse histological features, including extracapsular spread,...