You searched for "intervention"

917 results found

PD-1 and PD-L1 in exenteration specimens

This is an immunohistochemical study looking at variation in the expression of the programmed death-1 receptor (PD-1) and the programmed cell death ligand-1 (PD-L1), comparing cutaneous malignancies which invaded the orbit with uncomplicated nodular basal cell carcinomas. The authors retrospectively...

Post-treatment advice following botulinum toxin injections

The author gives a detailed review of the advice that is routinely offered to patients following treatment with botulinum toxin, as well as the available evidence to substantiate current recommendations. There is a detailed description of the mechanism of action...

Transgender facial surgery

In this review article the author outlines the various elements of this subspecialty, with reference to published literature and his own clinical experience in the field. The article does not present new data, and lacks the detail necessary to appeal...

The relevance of rhinoplasty and septorhinoplasty from the commissioner’s point of view

The rising costs of running the National Health Service and its overburdened resources has led to the constant monitoring of the low clinical value treatments. The operations of rhinoplasty and septorhinoplasty inevitably fall into this group and are subject to...

Improving the anatomical understanding of the causation of fine lines

An interesting piece which explores the current evidence of the factors that are thought to lead to facial ageing through fine lines. The author outlines a detailed discussion of the many intrinsic factors which can lead to the emergence of...

Combined Vismodegib and Mohs surgery

This is a report of eight patients with locally advanced periocular basal cell carcinoma who were treated with Vismodegib prior to Mohs micrographic surgery. The rationale for the combined treatment plan was that long-term Vismodegib is poorly tolerated due to...

Corneal neurotisation with an allograft

This is the first reported use of an acellular nerve allograft for corneal neurotisation. Seven patients received a 7cm long commercially prepared acellular nerve allograft. This was coapted to a functioning supratrochlear, supraorbital or infraorbital nerve and then tunnelled to...

The value of bariatric specific chart to initiate resuscitation

This is an interesting well written retrospective analysis of resuscitation in bariatric patients, but the study has two significant flaws. The first flaw is that parklands formula, with estimate from lund browder charts, is a guide and a best estimate...

The value of bariatric specific chart to initiate resuscitation of adult bariatric burns

This is an interesting well written retrospective analysis of resuscitation in bariatric patients, but the study has two significant flaws. The first flaw is that parkland’s formula, with estimate from lund browder charts is a guide and a best estimate...

CD73 in aggressive basal cell carcinoma

This is a retrospective review looking at levels of CD73 in aggressive basal cell carcinomas (BCCs) that invade the orbit. Eleven patients who underwent orbital exenteration for invasion by BCCs were compared with 10 matched controls who had simple nodular...

UK allergy crisis: deploy the ‘LIMED’ mnemonic

In response to the revelation that allergies now cost the NHS approximately £900 million pounds per year, Professor Frame and colleagues in Chelmsford explain why the mnemonic ‘LIED’ needs to be updated.

The role of expert witnesses in miscarriages of justice

‘Expert’ witnesses sometimes make mistakes. Great weight is often placed on expert evidence. The more esoteric the area of expertise, the greater the possibility of error. It follows that expert evidence sometimes leads to miscarriages of justice. Plastic surgery is...