Journal Reviews
Comparison of intralesional verapamil versus intralesional corticosteroids in treatment of keloids and hypertrophic scars
This paper by Abedini et al., is a randomised observer blinded controlled trial comparing the efficacy, safety profile, and recurrence rates of intralesional verapamil versus intralesional triamcinolone acetonide in the treatment of keloid and hypertrophic scars. Whilst corticosteroids represent the...
A single blinded RCT comparing triamcinolone with 5-FU treatment for keloid scars
This single blinded randomised controlled trial (RCT) compared 43 patients with 50 symptomatic keloids were were randomised to two matched groups of 25 scars, receiving either flurouracil (5-FU) or current first-line treatment, triamcinolone (TAC). The surgeon administering the injectable treatments...
A possible role for adipose tissue-derived stem cells in modulation of keloid scarring
Keloid scarring remains a challenging clinical problem due to both resistance to treatment as well as high rates of recurrence. Research into possible treatments is also hindered by keloid scarring being a uniquely human phenomenon. Recent evidence supports a role...
Management of keloid and hypertrophic scars
The management of keloid and hypertrophic scars is commonplace in all burns and plastic surgery outpatient clinics, and in this paper the authors review many of the current treatments available for this difficult problem. They start with an introduction about...
Ultrastructural changes in keloid scars
One of the most intriguing and infuriating problems confronting plastic surgeons is the occurrence of hypertrophic and keloid scars, in some patients – particularly black Africans – but not in others. Many theories have been proposed regarding the cause of...
