Journal Reviews

Free flap reconstruction in stage 3 bisphosphonate related osteonecrosis

8 October 2014 | | Maxillofacial Surgery | Bisphosphonates, Fibula free flap, Iliac crest free flap, Osteonecrosis

There is no widely accepted gold standard for the treatments of bisphosphonate-related osteonecrosis (BRONJ). Whereas the lesser stages of this BRONJ seem to respond well to conservative and minimal invasive therapies there is controversy regarding the treatment of the later...

Delayed intraoral wound healing in patients on bisphosphonates

11 February 2014 | | General Plastic Surgery, Maxillofacial Surgery | Bisphosphonate, Bisphosphonate related osteonecrosis of jaw, Oral bisphosphonate, Tooth extraction

Since Marx first described bisphosphonate related osteonecrosis of the jaw (BRONJ), the literature is now replete with cases of BRONJ. There are no internationally accepted protocols. A three month cessation of drug treatment, a ‘drug holiday’ has been advocated. The...